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RESOMER 生物可降解聚合物

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關(guān)鍵字：RESOMER 生物可降解聚合物 RESOMER 是贏創(chuàng)旗下一系列生物可降解聚合物的商品名。這類聚合物由丙交酯和乙交酯聚合而成。通過(guò)調(diào)整分子量，單體比例或加入其它單體，在植入或注射后在人體組織內(nèi)按照一定速率降解。體液能將聚合物水解為低聚體甚至為羥基酸單體，最終為人體代謝。RESOMER?在多種應(yīng)用中均表現(xiàn)出了良好的生物相容性：例如：整形外科固定件，提供粉末形態(tài)供藥物制劑使用。RESOMER穩(wěn)定性考察表明聚合物在合適的條件下能長(zhǎng)期存放。具體產(chǎn)品如下：名稱分子量粘性用途 Tg [℃] Tm [℃] 末端基 RESOMER L 206 S Poly(L-lactide) -- 0.8 - 1.2 Medical Device 60 - 65 180 - 185 alkyl ester RESOMER R 202 S Poly(D,L-lactide) 10,000 - 18,000 0.16 - 0.24 Controlled Release 38 - 42 amorphous alkyl ester RESOMER R 202 H Poly(D,L-lactide) 10,000 - 18,000 0.16 - 0.24 Controlled Release 44 - 48 amorphous free carboxylic acid RESOMER R 203 S Poly(D,L-lactide) 18,000 - 28,000 0.25 - 0.35 Controlled Release 46 - 50 amorphous Alkyl ester RESOMER R 203 H Poly(D,L-lactide) 18,000 - 28,000 0.25 - 0.35 Controlled Release 48 - 52 amorphous free carboxylic acid RESOMER RG 502 Poly(D,L-lactide-co-glycolide) 50:50 7,000 - 17,000 0.16 - 0.24 Controlled Release 42 - 46 amorphous alkyl ester RESOMER RG 502 H Poly(D,L-lactide-co-glycolide) 50:50 7,000 - 17,000 0.16 - 0.24 Controlled Release 42 - 46 amorphous free carboxylic acid RESOMER RG503 Poly(D,L-lactide-co-glycolide) 50:50 24,000 - 38,000 0.32 - 0.44 Controlled Release - amorphous alkyl ester RESOMER RG 503 H Poly(D,L-lactide-co-glycolide) 50:50 24,000 - 38,000 0.32 - 0.44 Controlled Release 44 - 48 amorphous free carboxylic acid RESOMER RG504 Poly(D,L-lactide-co-glycolide) 50:50 38,000 - 54,000 0.45 - 0.60 Controlled Release - amorphous alkyl ester RESOMER RG 504 H Poly(D,L-lactide-co-glycolide) 50:50 38,000 - 54,000 0.45 - 0.60 Controlled Release 46 - 50 amorphous free carboxylic acid RESOMER RG505 Poly(D,L-lactide-co-glycolide) 50:50 54,000 - 69,000 0.61 - 0.74 Controlled Release - amorphous alkyl ester RESOMER RG 653 H Poly(D,L-lactide-co-glycolide) 65:35 24,000 - 38,000 0.32 - 0.44 Controlled Release 46 - 50 amorphous free carboxylic acid RESOMER RG 752 H Poly(D,L-lactide-co-glycolide) 75:25 4,000 - 15,000 0.14 - 0.22 Controlled Release 42 - 46 amorphous free carboxylic acid RESOMER RG 756 S Poly(D,L-lactide-co-glycolide) 75:25 76,000 - 116,000 0.71 - 1.0 Controlled Release 49 - 55 amorphous alkyl ester RESOMER RG858 S Poly(D,L-lactide-co-glycolide) 85:15 190,000 - 240,000 1.3 - 1.7 Controlled Release - amorphous alkyl ester RESOMER X Polydioxanone -- 1.5 - 2.2 (0.1% in HFIP, 30℃) Medical Device -10 - -5 110 - 115 --

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